Новое исследование о сухом голодании

[Олег1099]

Сообщение от Вадим Асадулин

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НАЧНУ ПО ЧАСТЯМ, В ПОРЯДКЕ ОЧЕРЕДНОСТИ, ДЕЙСТВИТЕЛЬНО ПОКА НЕ ПЕРЕКИНУЛИ В ПЛАТНЫЕ, ПОЗЖЕ ПЕРЕВЕДЕМ ВСЕМ НАРОДОМ-
Juice and water fasting in the form of Buchinger fasting has been studied and therapeutically applied from the beginning of the 20th century to the present [1,2,3]. In the last decade, however, increasing evidence has proved benefits of fluid restriction against polyposia [4,5]. Increased fluid intake was reported to decrease glomerular filtration rate (GFR) [6]. Fluid restriction was found to be beneficial: (a) in surgery, since it reduced complications after partial colectomy [7], (b) in nephrology, since it improved the prognosis of chronic kidney disease (CKD) [8,9], and (c) in intensive care medicine, since it improved the treatment of lung injury and acute respiratory distress syndrome (ARDS) [10].

However, little is known about food and water deprivation (FWD), and no systematic study has been published investigating anthropometric, hemodynamic, metabolic, and renal responses during FWD. FWD can either occur due to natural or man-caused disasters (earthquakes, war, etc.) or it can be performed voluntarily for religious reasons. From the 1st century A.D. up to the present, orthodox Christians, particularly monks and nuns, practice FWD for several days in the context of Easter fasting. In the 6th and 7th century A.D., famous Byzantine ascetics reported on the hindering effect of polyposia in their descriptions of the spiritual struggle [11] and recommended FWD as potent measure of corporeal and spiritual clarification [12]. In the 5th century B.C., Hippocrates as physician generally prescribed oligoposia and applied FWD in the treatment of acute maladies and chronic diseases [13]. Recently, many volatile compounds, such as acetone, dichloromethane, and toluene, have been detected in the exhaled air of Athos monks after 63 h of FWD [14].

Numerous studies have documented the correlation between anthropometric parameters and disease risk factors. Neck circumference (NC) increase is associated with increase of the risk factors of sleep apnea [15,16] and insulin resistance [17]. Waist circumference (WC) increase is associated with increase of the risks of death [18,19], cardiovascular disease (CVD) [20,21], diabetes [19], metabolic syndrome [17,21,22], cancer [23], chronic respiratory disease [24,25], sleep apnea [16], and kidney stone formation [26]. Waist-to-height ratio (WHtR) increase is associated with increase of the risks of metabolic syndrome [22], CVD [20,21], and cancer [23]. Waist-to-hip ratio (WHR) increase is associated with increase of the risks of mortality [18], CVD [20], and cancer [23].

The objectives of this study were to a) investigate the effects of FWD on safety-related hemodynamic, metabolic, and renal parameters, b) to complement the set of known anthropometric parameters with new ones, and c) to evaluate the changes of new and old anthropometric parameters during FWD.